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Oclacitinib

Catalog No.: 16122705
Cas No.: 1640292-55-2
Purity : 98% 
16122705 - Oclacitinib | CAS 1640292-55-2

Catalog number : 16122705

CAS number : 1640292-55-2

分子式 : C15H23N5O2S.C4H4O4 

分子量 : 453.51 

Iupac 化学名称 : Oclacitinib 

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同义词PF-03394197 
英文同义词PF-03394197 
分子式C15H23N5O2S.C4H4O4 
分子量453.51 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases. PF-03394197 is most potent at inhibiting JAK1. PF-03394197 also inhibits the function of JAK1-dependent cytokines involved in allergy and inflammation as well as pruritus. PF-03394197 has minimal effects on cytokines which does not activate the JAK1 enzyme in cells 

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