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OSI-027 HCl salt

Catalog No.: 161009007
Cas No.: 936890-98-1
Purity : 98% by HPLC 
161009007 - OSI-027 HCl salt | CAS 936890-98-1

Catalog number : 161009007

CAS number : 936890-98-1

分子式 : C21H23ClN6O3 

分子量 : 442.9 

Iupac 化学名称 : 4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid hydrochloride. 

Smile : COc1cccc2c1[nH]c(c2)c3c4c(ncnn4c(n3)C5CCC(CC5)C(=O)O)N.Cl

InChiKey : NVPWJMHJZINDTG-UHFFFAOYSA-N

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同义词mTOR kinase inhibitor OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is a serine/threonine kinase that is upregulated in some tumors and plays an important role downstream in the PI3K/Akt/mTOR signaling pathway. Check for active clinical trials or closed clinical trials using this agent. 
英文同义词mTOR kinase inhibitor OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is a serine/threonine kinase that is upregulated in some tumors and plays an important role downstream in the PI3K/Akt/mTOR signaling pathway. Check for active clinical trials or closed clinical trials using this agent. 
分子式C21H23ClN6O3 
分子量442.9 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCOc1cccc2c1[nH]c(c2)c3c4c(ncnn4c(n3)C5CCC(CC5)C(=O)O)N.Cl
InChiKeyNVPWJMHJZINDTG-UHFFFAOYSA-N
InChiInChI=1S/C21H22N6O3.ClH/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29;/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24);1H
MDLMFCD18251429
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mTOR kinase inhibitor OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is a serine/threonine kinase that is upregulated in some tumors and plays an important role downstream in the PI3K/Akt/mTOR signaling pathway. Check for active clinical trials or closed clinical trials using this agent. 

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