Nitroxoline
Catalog number : 16122719
CAS number : 4008-48-4
分子式 : C9H6N2O3
分子量 : 190.16
Iupac 化学名称 : Nitroxoline
Smile : c1cc2c(ccc(c2nc1)[N+](=O)[O-])O
InChiKey : GBFQOBPPJULZSN-UHFFFAOYSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| 同义词 | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
|---|---|
| 英文同义词 | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
| 分子式 | C9H6N2O3 |
| 分子量 | 190.16 |
| 外观 | crystalline solid |
| 纯度 | 98% |
| 可溶性 | Soluble in DMSO |
| 存储 | 3 years -20ºCpowder |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| Smile | c1cc2c(ccc(c2nc1)[N+](=O)[O-])O |
| InChiKey | GBFQOBPPJULZSN-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)9-6(8)2-1-5-10-9/h1-5,12H |
| MDL | MFCD06015325 |
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases.Nitroxoline significantly reduces extracellular DQ-collagen IV degradation by all evaluated cancer cell lines using spectrofluorimetry. Nitroxoline also markedly decreases tumor cell invasion monitored in real time and reduces the invasive growth of multicellular tumor spheroids, used as a 3D in vitromodel of tumor invasion. Endothelial tube formation is significantly reduced by nitroxoline in an in vitro angiogenesis assay
