Nitroxoline
编号: 16122719
Cas号: 4008-48-4
纯度: 98%
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases.Nitroxoline significantly reduces extracellular DQ-collagen IV degradation by all evaluated cancer cell lines using spectrofluorimetry. Nitroxoline also markedly decreases tumor cell invasion monitored in real time and reduces the invasive growth of multicellular tumor spheroids, used as a 3D in vitromodel of tumor invasion. Endothelial tube formation is significantly reduced by nitroxoline in an in vitro angiogenesis assay
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化学信息
| 名称 | Nitroxoline |
|---|---|
| Iupac 化学名称 | Nitroxoline |
| 同义词 | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
| 英文同义词 | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
| 分子式 | C9H6N2O3 |
| 分子量 | 190.16 |
| Smile | c1cc2c(ccc(c2nc1)[N+](=O)[O-])O |
| InChiKey | GBFQOBPPJULZSN-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)9-6(8)2-1-5-10-9/h1-5,12H |
| Cas号 | 4008-48-4 |
| MDL | MFCD06015325 |
| 相关CAS号 |
订购信息
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