Nitroxoline
Catalog No: 16122719
CAS Number: 4008-48-4
Purity: 98%
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases.Nitroxoline significantly reduces extracellular DQ-collagen IV degradation by all evaluated cancer cell lines using spectrofluorimetry. Nitroxoline also markedly decreases tumor cell invasion monitored in real time and reduces the invasive growth of multicellular tumor spheroids, used as a 3D in vitromodel of tumor invasion. Endothelial tube formation is significantly reduced by nitroxoline in an in vitro angiogenesis assay
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Chemical Information
| Name | Nitroxoline |
|---|---|
| Iupac Chemical Name | Nitroxoline |
| Synonyms | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
| 英文同义词 | 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline |
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 |
| Smile | c1cc2c(ccc(c2nc1)[N+](=O)[O-])O |
| InChiKey | GBFQOBPPJULZSN-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)9-6(8)2-1-5-10-9/h1-5,12H |
| CAS Number | 4008-48-4 |
| MDL | MFCD06015325 |
| 相关CAS号 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| 处理方式 | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
