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Neflamapimod

Catalog No.: 1791317
Cas No.: 209410-46-8
Purity : 98.0%
1791317 - Neflamapimod | CAS 209410-46-8

Catalog number : 1791317

CAS number : 209410-46-8

分子式 : C19H9Cl2F2N3OS

分子量 : 436.26

Iupac 化学名称 : 5-(2,6-Dichlorophenyl)-2-(2,4-difluorophenylsulfanyl)-6H-pyrimido[3,4-b]pyridazin-6-one

Smile : ClC1=C(C(=CC=C1)Cl)C=1C(N=CN2N=C(C=CC21)SC2=C(C=C(C=C2)F)F)=O

InChiKey : VEPKQEUBKLEPRA-UHFFFAOYSA-N

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同义词VX-745; VX 745; VX745; VRT-031745, VD-31745; Neflamapimod.
英文同义词VX-745; VX 745; VX745; VRT-031745, VD-31745; Neflamapimod.
分子式C19H9Cl2F2N3OS
分子量436.26
外观类白色至白色固体
纯度98.0%
可溶性可溶于DMSO;不溶于水
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileClC1=C(C(=CC=C1)Cl)C=1C(N=CN2N=C(C=CC21)SC2=C(C=C(C=C2)F)F)=O
InChiKeyVEPKQEUBKLEPRA-UHFFFAOYSA-N
InChiInChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H
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Neflamapimod,也称为VX-745,VRT-031745和VD-31745,是高度有效的和选择性的p38α抑制剂(IC50 = 10 nm)。

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