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Necrostatin 2 racemate

编号: 6111411
Cas号: 852391-15-2
纯度: 98% 

Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.

Necrostatin 2 is a potent in vitro necroptosis inhibitors (exemplified by 1, EC50-0.05 uM) that also were efficacious in an animal model of ischemic stroke. Many Necroptosis inhibitor derivatives are designed for researchers.
Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. It can be induced in a FADD-deficient variant of human Jurkat T cells treated with TNF-a. 5-(1H-Indol-3-ylmethyl)-2-thiohydantoins and 5-(1H-indol-3-ylmethyl)hydantoins were found to be potent necroptosis inhibitors (called necrostatins).

 

仅供研究使用。 我们不向患者出售。

化学信息

名称Necrostatin 2 racemate
Iupac 化学名称Necrostatin 2 racemate 
同义词Necrostatin-2 racemate 
英文同义词Necrostatin-2 racemate 
分子式C13H12ClN3O2 
分子量277.71 
InChiKey
InChi
Cas号852391-15-2
相关CAS号

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

6111411 - Necrostatin 2 racemate | CAS 852391-15-2

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