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Naquotinib游离

Catalog No.: 1812297
Cas No.: 1448232-80-1
Purity : >98%
1812297 - Naquotinib游离 | CAS 1448232-80-1

Catalog number : 1812297

CAS number : 1448232-80-1

分子式 : C30H42N8O3

分子量 : 562.719

Iupac 化学名称 : (R)-5-((1-acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide

Smile : O=C(C1=NC(CC)=C(O[C@H]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N

InChiKey : QKDCLUARMDUUKN-XMMPIXPASA-N

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同义词ASP8273; ASP-8273; ASP 8273; Naquotinib free base.
英文同义词ASP8273; ASP-8273; ASP 8273; Naquotinib free base.
分子式C30H42N8O3
分子量562.719
外观 类白色至白色固体
纯度>98%
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileO=C(C1=NC(CC)=C(O[C@H]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N
InChiKeyQKDCLUARMDUUKN-XMMPIXPASA-N
InChiInChI=1S/C30H42N8O3/c1-4-25-30(41-24-12-15-38(20-24)26(39)5-2)34-29(27(33-25)28(31)40)32-21-6-8-22(9-7-21)36-13-10-23(11-14-36)37-18-16-35(3)17-19-37/h5-9,23-24H,2,4,10-20H2,1,3H3,(H2,31,40)(H,32,34)/t24-/m1/s1
Coming soon.
Naquotinib,又称ASP8273,是一种口服、不可逆、第三代、突变选择、表皮生长因子受体(EGFR)抑制剂,具有潜在的抗肿瘤活性。

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