This compound is the hydrochloride salt of NVP-LDE225, which is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | NVP-LDE225 Hydrochloride |
同义词 | N-[6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide;hydrochloride |
英文同义词 | N-[6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide;hydrochloride |
分子式 | C26H27ClF3N3O3 |
分子量 | 521.959 |
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InChi | |
Cas号 | 1218778-76-7 |
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外观性状 | Solid powder |
纯度 | 98% |
存储 | -20 ℃ for 3 years |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
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