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NVP-BAG956

Catalog No.: 52605
Cas No.: 853910-02-8
Purity : 98% 
52605 - NVP-BAG956 | CAS 853910-02-8

Catalog number : 52605

CAS number : 853910-02-8

分子式 : C28H21N5 

分子量 : 427.5 

化学名称 : NVP-BAG956

Smile : Cc1nc2cnc3ccc(cc3c2n1c4ccc(cc4)C(C)(C)C#N)C#Cc5cccnc5

InChiKey : GVPAGJWVBUZHNQ-UHFFFAOYSA-N

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分子式C28H21N5 
分子量427.5 
纯度98% 
SmileCc1nc2cnc3ccc(cc3c2n1c4ccc(cc4)C(C)(C)C#N)C#Cc5cccnc5
InChiKeyGVPAGJWVBUZHNQ-UHFFFAOYSA-N
InChiInChI=1S/C28H21N5/c1-19-32-26-17-31-25-13-8-20(6-7-21-5-4-14-30-16-21)15-24(25)27(26)33(19)23-11-9-22(10-12-23)28(2,3)18-29/h4-5,8-17H,1-3H3
MDLMFCD16618394
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NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively. 

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