+86-27-65522453 sales@sun-shinechem.com

NT-157

Catalog No.: 51508
Cas No.: 1384426-12-3
Purity : 98% 
51508 - NT-157 | CAS 1384426-12-3

Catalog number : 51508

CAS number : 1384426-12-3

分子式 : C16H14BrNO5S 

分子量 : 412.26 

Iupac 化学名称 : (E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide 

Smile : S=C(NCC1=CC(O)=C(O)C(O)=C1)/C=C/C2=CC(O)=C(O)C(Br)=C2

InChiKey : NIPUPOUEGOSAAO-OWOJBTEDSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词NT157;NT 157 
英文同义词NT157;NT 157 
分子式C16H14BrNO5S 
分子量412.26 
外观yellow solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileS=C(NCC1=CC(O)=C(O)C(O)=C1)/C=C/C2=CC(O)=C(O)C(Br)=C2
InChiKeyNIPUPOUEGOSAAO-OWOJBTEDSA-N
InChiInChI=1S/C16H14BrNO5S/c17-10-3-8(4-11(19)15(10)22)1-2-14(24)18-7-9-5-12(20)16(23)13(21)6-9/h1-6,19-23H,7H2,(H,18,24)/b2-1+
Coming soon.

NT157 is a small-molecule tyrphostin targeting human IRSes.

References:
1. Krueckl SL et al. Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res. 2004;64:8620.
2. Gleave M, Cox M, Wang YZ: Cell biology of prostate cancer and molecular targets. In Drug Management of Prostate Cancer. (Figg, Chau, Small, Eric, Eds.) Humana Press, Springer New York Dordrecht Heidelberg London, 2010.
3. Reuveni H et al. Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment. Cancer Res 2013;73:4383.



 

1384426-12-3 - Request Bulk Quote

×
1384426-12-3 - Request Bulk Quote
Change