NQDI-1
编号: 16122772
Cas号: 175026-96-7
纯度: 98%
NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.NQDI 1 inhibits the expression of ASK1 and downstream targets in the HI model. It also inhibits injury and apoptosis in the brain cortex. Intracerebroventricularly injection of NQDI 1 after neonatal rats brain HI significantly attenuates acute HI cerebral injury by inhibiting cell apoptosis. The treatment of NQDI-1 markedly inhibits the expression of ASK1 following HI in the perinatal rat, accompanied by a decrease of p-JNK, p-c-Jun, p53 and caspase 3, which were the downstream targets of ASK1
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | NQDI-1 |
|---|---|
| Iupac 化学名称 | NQDI-1 |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C19H13NO4 |
| 分子量 | 319.31 |
| Smile | CCOC(=O)c1c-2c3c(cccc3[nH]c1=O)C(=O)c4c2cccc4 |
| InChiKey | UFJGFNHRMPMALC-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22) |
| Cas号 | 175026-96-7 |
| MDL | MFCD03265970 |
| 相关CAS号 |
订购信息
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