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Mobocertinib free base

编号: 20111803
Cas号: 1847461-43-1
纯度: 98% Min.

 Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.

仅供研究使用。 我们不向患者出售。

化学信息

名称 Mobocertinib free base
Iupac 化学名称propan-2-yl 2-[4-{[2-(dimethylamino)ethyl](methyl)amino}-2-methoxy-5-(prop-2-enamido)anilino]-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
同义词 Mobocertinib; TAK-788; TAK 788; TAK788; AP32788; AP-32788; AP 32788;Mobocertinib free base
英文同义词 Mobocertinib; TAK-788; TAK 788; TAK788; AP32788; AP-32788; AP 32788;Mobocertinib free base
分子式C32H39N7O4
分子量585.71
SmileO=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C
InChiKeyAZSRSNUQCUDCGG-UHFFFAOYSA-N
InChi InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)
Cas号1847461-43-1
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状固体粉末
纯度98% Min.
存储短期(几天到几周)为0-4摄氏度,长期(几个月)为-20摄氏度
可溶性可溶于DMSO
处理方式
运输条件作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

20111803 -  Mobocertinib free base | CAS 1847461-43-1

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