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Mitoxantrone HCl

编号: 16123051
Cas号: 65271-80-9
纯度: 98% 

Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

 

仅供研究使用。 我们不向患者出售。

化学信息

名称Mitoxantrone HCl
Iupac 化学名称Mitoxantrone HCl 
同义词DHAQ; CL-232325; CL 232325; CL232325; Mitozantrone; Mitoxantrone HCl; Mitoxantrone dihydrchloride; US brand name: Novantrone. Foreign brand names: Mitroxone; Neotalem; Onkotrone; Pralifan. 
英文同义词DHAQ; CL-232325; CL 232325; CL232325; Mitozantrone; Mitoxantrone HCl; Mitoxantrone dihydrchloride; US brand name: Novantrone. Foreign brand names: Mitroxone; Neotalem; Onkotrone; Pralifan. 
分子式C22H28N4O6 
分子量444.48 
Smilec1cc(c2c(c1NCCNCCO)C(=O)c3c(ccc(c3C2=O)O)O)NCCNCCO.Cl
InChiKeyMKCBCZDNNZPMCG-UHFFFAOYSA-N
InChiInChI=1S/C22H28N4O6.ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;/h1-4,23-30H,5-12H2;1H
Cas号65271-80-9
MDLMFCD03086914
相关CAS号

订购信息

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16123051 - Mitoxantrone HCl | CAS 65271-80-9

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