Mavacamten, also known as SAR-439152 and MYK-461, is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy.
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名称 | Mavacamten |
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Iupac 化学名称 | (S)-3-isopropyl-6-((1-phenylethyl)amino)pyrimidine-2,4(1H,3H)-dione |
同义词 | SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; Mavacamten. |
英文同义词 | SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; Mavacamten. |
分子式 | C15H19N3O2 |
分子量 | 273.336 |
Smile | O=C1N(C(C)C)C(C=C(N[C@H](C2=CC=CC=C2)C)N1)=O |
InChiKey | RLCLASQCAPXVLM-NSHDSACASA-N |
InChi | InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1 |
Cas号 | 1642288-47-8 |
相关CAS号 |
包装 | 价格 | 库存 | 纯度 | 备货期 |
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大货 | 询价 | 询价 | 询价 |
外观性状 | Off-white solid to white solid |
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纯度 | >98% |
存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
海关编码 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |