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Masitinib

Catalog No.: 121508
Cas No.: 790299-79-5
Purity : 98% 
121508 - Masitinib | CAS 790299-79-5

Catalog number : 121508

CAS number : 790299-79-5

分子式 : C28H30N6OS 

分子量 : 498.64 

Iupac 化学名称 : 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide 

Smile : CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5

InChiKey : WJEOLQLKVOPQFV-UHFFFAOYSA-N

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同义词AB-1010; AB 1010; AB1010 
英文同义词AB-1010; AB 1010; AB1010 
分子式C28H30N6OS 
分子量498.64 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
InChiKeyWJEOLQLKVOPQFV-UHFFFAOYSA-N
InChiInChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)
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Masitinib is a novel inhibitor for Kit and PDGFR/ with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms.
 

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