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MT-DADMe-ImmA

Catalog No.: 703301
Cas No.: 653592-04-2
Purity : 98% by HNMR/HPLC 
703301 - MT-DADMe-ImmA | CAS 653592-04-2

Catalog number : 703301

CAS number : 653592-04-2

分子式 : C13H19N5OS 

分子量 : 293.4 

Iupac 化学名称 : (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-4-((methylthio)methyl)pyrrolidin-3-ol 

Smile : CSC[C@@H]1[C@@H](O)CN(CC2=CNC3=C(N)N=CN=C32)C1

InChiKey : NTHMDFGHOCNNOE-ZJUUUORDSA-N

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同义词MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl 
英文同义词MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl 
分子式C13H19N5OS 
分子量293.4 
外观类白色至白色固体
纯度98% by HNMR/HPLC 
可溶性可溶于DMSO;不溶于水
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileCSC[C@@H]1[C@@H](O)CN(CC2=CNC3=C(N)N=CN=C32)C1
InChiKeyNTHMDFGHOCNNOE-ZJUUUORDSA-N
InChiInChI=1S/C13H19N5OS/c1-20-6-9-4-18(5-10(9)19)3-8-2-15-12-11(8)16-7-17-13(12)14/h2,7,9-10,15,19H,3-6H2,1H3,(H2,14,16,17)/t9-,10+/m1/s1
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Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) 是一种5 -甲基硫腺苷磷酸化酶(MTAP)的86-pm抑制剂抑制剂。采用MT-DADMe-ImmA和MTA治疗培养细胞,抑制MTAP,增加细胞MTA浓度,减少多胺,并诱导FaDu和Cal27、两头和颈部鳞状细胞癌细胞系的凋亡。

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