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MMAF (Monomethyl auristatin F)

Catalog No.: 17030611
Cas No.: 745017-94-1
Purity : 98% 

一甲基澳瑞他汀 F(MMAF)是一种合成抗肿瘤药物。它是一些实验性抗癌抗体药物结合物中的一部分,如vorsetuzumab mafodotin和SGN-CD19A。

For research use only. We do not sell to patients.

Chemical Information

名称MMAF (Monomethyl auristatin F)
Iupac 化学名称((2R,3R)-3-((2S)-1-((3R,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine 
同义词Monomethyl auristatin F; MMAF 
英文同义词Monomethyl auristatin F; MMAF 
分子式C39H65N5O8 
分子量731.98 
SmileCN(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C([C@@H](CC(=O)N1[C@@H](CCC1)[C@@H]([C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)C)OC)OC)[C@H](CC)C
InChiKeyMFRNYXJJRJQHNW-NARUGQRUSA-N
InChiInChI=1S/C39H65N5O8/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-17-14-13-15-18-27/h13-15,17-18,23-26,28-30,32-35,40H,12,16,19-22H2,1-11H3,(H,41,46)(H,42,47)(H,49,50)/t25-,26+,28-,29-,30+,32-,33-,34?,35+/m0/s1
Cas号745017-94-1
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Ordering Information

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Formulation类白色至白色固体
纯度98% 
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO;不溶于水
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

17030611 - MMAF (Monomethyl auristatin F) | CAS 745017-94-1

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