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MK-8033

Catalog No.: 011801
Cas No.: 1001917-37-8
Purity : 98% 
011801 - MK-8033 | CAS 1001917-37-8

Catalog number : 011801

CAS number : 1001917-37-8

分子式 : C25H21N5O3S 

分子量 : 471.531 

Iupac 化学名称 : 1-[2-(1-methylpyrazol-4-yl)-11-oxobenzo[1,2]cyclohepta[2,4-b]pyridin-9-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide 

Smile : CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)C(=O)C3=C2

InChiKey : VMJFTOSOFDEKTM-UHFFFAOYSA-N

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同义词MK 8033; MK8033 
英文同义词MK 8033; MK8033 
分子式C25H21N5O3S 
分子量471.531 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)C(=O)C3=C2
InChiKeyVMJFTOSOFDEKTM-UHFFFAOYSA-N
InChiInChI=1S/C25H21N5O3S/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32,33)29-14-21-4-2-3-9-26-21/h2-13,15,29H,14,16H2,1H3
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MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. 

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