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MK-5108

Catalog No.: 121504
Cas No.: 1010085-13-8
Purity : 98% 
121504 - MK-5108 | CAS 1010085-13-8

Catalog number : 121504

CAS number : 1010085-13-8

分子式 : C22H21ClFN3O3S 

分子量 : 461.937 

Iupac 化学名称 : 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid 

Smile : C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

InChiKey : LCVIRAZGMYMNNT-UHFFFAOYSA-N

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同义词MK 5108; VX-689; VX 689; MK5108; VX689 
英文同义词MK 5108; VX-689; VX 689; MK5108; VX689 
分子式C22H21ClFN3O3S 
分子量461.937 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O
InChiKeyLCVIRAZGMYMNNT-UHFFFAOYSA-N
InChiInChI=1S/C22H21ClFN3O3S/c23-16-4-2-5-17(19(16)24)30-15-7-9-22(10-8-15,20(28)29)13-14-3-1-6-18(26-14)27-21-25-11-12-31-21/h1-6,11-12,15H,7-10,13H2,(H,28,29)(H,25,26,27)
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MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM; 220- and 190-fold more selective for Aurora A than Aurora B/C. 

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