MK-4827
编号: 123007
Cas号: 1038915-60-4
纯度: 98%
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | MK-4827 |
|---|---|
| Iupac 化学名称 | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| 同义词 | Niraparib; MK 4827; MK4827 |
| 英文同义词 | Niraparib; MK 4827; MK4827 |
| 分子式 | C19H20N4O |
| 分子量 | 320.388 |
| Smile | C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
| InChiKey | PCHKPVIQAHNQLW-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24) |
| Cas号 | 1038915-60-4 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
