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MK-1775

Catalog No.: 011110
Cas No.: 955365-80-7
Purity : 98% 
011110 - MK-1775 | CAS 955365-80-7

Catalog number : 011110

CAS number : 955365-80-7

分子式 : C27H32N8O2 

分子量 : 500.595 

Iupac 化学名称 : 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one 

Smile : CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

InChiKey : BKWJAKQVGHWELA-UHFFFAOYSA-N

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同义词AZD-1775; AZD1775; AZD 1775 
英文同义词AZD-1775; AZD1775; AZD 1775 
分子式C27H32N8O2 
分子量500.595 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
InChiKeyBKWJAKQVGHWELA-UHFFFAOYSA-N
InChiInChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-17H2,2-4H3,(H,28,29,31)
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MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA damage checkpoint. 

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