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MK-0812

Catalog No.: 2017080111
Cas No.: 624733-88-6
Purity : 98.0% 

MK-0812是一种有效、选择性的CCR2拮抗剂。趋化因子受体2(CCR2)是单核细胞迁移到炎症组织的中心。

For research use only. We do not sell to patients.

Chemical Information

名称MK-0812
Iupac 化学名称((1S,3R)-1-isopropyl-3-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)cyclopentyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone 
同义词MK-0812|MK 0812|MK0812. 
英文同义词MK-0812|MK 0812|MK0812. 
分子式C24H34F3N3O3 
分子量469.5492 
SmileC(C)(C)[C@]1(C[C@@H](CC1)N[C@@H]1[C@@H](COCC1)OC)C(=O)N1CC=2C=C(C=NC2CC1)C(F)(F)F
InChiKeyMTMDXAIUENDNDL-RJSMDTJLSA-N
InChiInChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1
Cas号624733-88-6
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Ordering Information

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Formulation类白色至白色固体
纯度98.0% 
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO;不溶于水
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

2017080111 - MK-0812 | CAS 624733-88-6

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