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MIK665

Catalog No.: 191252
Cas No.: 1799631-75-6
Purity : >98%
191252 - MIK665  | CAS 1799631-75-6

Catalog number : 191252

CAS number : 1799631-75-6

分子式 : C47H44ClFN6O6S

分子量 : 875.4134

Iupac 化学名称 : (R)-2-((5-(3-chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)oxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid

Smile : O=C(O)[C@@H](CC1=C(OCC2=NC(C3=C(OC)C=CC=C3)=NC=C2)C=CC=C1)OC4=C5C(SC(C6=CC=C(F)C=C6)=C5C7=C(C)C(Cl)=C(OCCN8CCN(C)CC8)C=C7)=NC=N4

InChiKey : PKYIMGFMRFVOMB-LDLOPFEMSA-N

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同义词MIK665; MIK-665; MIK 665; S 64315; S-64315; S64315.
英文同义词MIK665; MIK-665; MIK 665; S 64315; S-64315; S64315.
分子式C47H44ClFN6O6S
分子量875.4134
外观 类白色至白色固体
纯度>98%
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileO=C(O)[C@@H](CC1=C(OCC2=NC(C3=C(OC)C=CC=C3)=NC=C2)C=CC=C1)OC4=C5C(SC(C6=CC=C(F)C=C6)=C5C7=C(C)C(Cl)=C(OCCN8CCN(C)CC8)C=C7)=NC=N4
InChiKeyPKYIMGFMRFVOMB-LDLOPFEMSA-N
InChiInChI=1S/C47H44ClFN6O6S/c1-29-34(16-17-38(42(29)48)59-25-24-55-22-20-54(2)21-23-55)40-41-45(51-28-52-46(41)62-43(40)30-12-14-32(49)15-13-30)61-39(47(56)57)26-31-8-4-6-10-36(31)60-27-33-18-19-50-44(53-33)35-9-5-7-11-37(35)58-3/h4-19,28,39H,20-27H2,1-3H3,(H,56,57)/t39-/m1/s1
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MIK665,又称s64315,诱导骨髓白血病细胞分化蛋白(mcl1;Bcl2-L-3),具有潜在的促凋亡和抗肿瘤活性。

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