MI-2 (MALT1 inhibitor)
编号: 16123047
Cas号: 1047953-91-2
纯度: 98%
MI-2 is a MALT1 inhibitor (IC50 = 5.84 M). MI-2 binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF-B activity induced by MALT1. Mucosa-associated-lymphoid-tissue lymphoma-translocation gene 1 (MALT1), a paracaspase and essential regulator for nuclear factor kB (NF-B) activation, plays an important role in innate and adaptive immunity. Suppression of MALT1 protease activity with small molecule inhibitors showed promising efficacies in subtypes of B cell lymphoma and improvement in experimental autoimmune encephalomyelitis model.
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化学信息
| 名称 | MI-2 (MALT1 inhibitor) |
|---|---|
| Iupac 化学名称 | MI-2 (MALT1 inhibitor) |
| 同义词 | MI 2; MI2 |
| 英文同义词 | MI 2; MI2 |
| 分子式 | C19H17Cl3N4O3 |
| 分子量 | 455.72 |
| InChiKey | |
| InChi | |
| Cas号 | 1047953-91-2 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
