Lubiprostone
编号: 16123037
Cas号: 333963-40-9
纯度: 98%
Lubiprostone, also known as RU-0211, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. It was initially approved by the U.S. Food and Drug Administration (FDA) in 2006. Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Lubiprostone |
|---|---|
| Iupac 化学名称 | Lubiprostone |
| 同义词 | RU-0211; RU 0211; RU0211; Lubiprostone. trade name Amitiza |
| 英文同义词 | RU-0211; RU 0211; RU0211; Lubiprostone. trade name Amitiza |
| 分子式 | C20H32F2O5 |
| 分子量 | 390.4678 |
| Smile | CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F |
| InChiKey | WGFOBBZOWHGYQH-MXHNKVEKSA-N |
| InChi | InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1 |
| Cas号 | 333963-40-9 |
| MDL | MFCD08444045 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
