L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC₅₀ values of 10 M and 10 M.). L67 significantly increased the cytotoxicity of DNA-damaging.
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化学信息
| 名称 | L67 |
| Iupac 化学名称 | L67 |
| 同义词 | L-67; L 67 |
| 英文同义词 | L-67; L 67 |
| 分子式 | C16H14Br2N4O4 |
| 分子量 | 486.12 |
| InChiKey | |
| InChi | |
| Cas号 | 325970-71-6 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |