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Kenpaullone

编号: 16122711
Cas号: 142273-20-9
纯度: 98% 

Kenpaullone is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs). It also inhibit glycogen synthase kinase 3 (GSK3) with IC50 of 0.23 M. Kenpaullone also induces the dephosphorylation of both GSK3 isoforms in SH-SY5Y cells and PC12 cells. Kenpaullone (20M) strongly suppresses the autophosphorylation of GSK3 at Tyr216 in vitro whether GSK3 is expressed in Sf21 cells or in E. coli 

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化学信息

名称Kenpaullone
Iupac 化学名称Kenpaullone 
同义词N/A 
英文同义词N/A 
分子式C16H11BrN2O 
分子量327.18 
Smilec1ccc2c(c1)-c3c(c4cc(ccc4[nH]3)Br)CC(=O)N2
InChiKeyQQUXFYAWXPMDOE-UHFFFAOYSA-N
InChiInChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
Cas号142273-20-9
MDLMFCD02683595
相关CAS号

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
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化学结构

16122711 - Kenpaullone | CAS 142273-20-9

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