KN-93 is a CaMKII inhibitor. KN-93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN-93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN-93 ameliorates levodopa-induced dyskinesia in a rat model of Parkinson's disease. KN-93 protects rat cerebral cortical neurons from N-methyl-D-aspartic acid-induced injury.
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化学信息
| 名称 | KN-93 phosphate |
| Iupac 化学名称 | KN-93 phosphate |
| 同义词 | KN93; KN 93; KN-93 |
| 英文同义词 | KN93; KN 93; KN-93 |
| 分子式 | C26H32ClN2O8PS |
| 分子量 | 599.0318 |
| InChiKey | |
| InChi | |
| Cas号 | 1188890-41-6 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |