K-7174
编号: 16123028
Cas号: 191089-59-5
纯度: 98%
K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. K-7174 kills bortezomib-resistant myeloma cells carrying a 5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib. K-7174 is also a GATA-specific inhibitor, which may have potential application in treating anemia of chronic disease.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | K-7174 |
|---|---|
| Iupac 化学名称 | 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride |
| 同义词 | K7174; K 7174; K-7174; K-7174-2HCl; K-7174 |
| 英文同义词 | K7174; K 7174; K-7174; K-7174-2HCl; K-7174 |
| 分子式 | C33H50Cl2N2O6 |
| 分子量 | 640.3 |
| Smile | Cl.Cl.COC=1C=C(C=C(C1OC)OC)/C=C/CCCN1CCN(CCC1)CCC\C=C\C1=CC(=C(C(=C1)OC)OC)OC |
| InChiKey | JKAQFPBRMVEHBD-CHBZAFCASA-N |
| InChi | InChI=1S/C33H48N2O6.2ClH/c1-36-28-22-26(23-29(37-2)32(28)40-5)14-9-7-11-16-34-18-13-19-35(21-20-34)17-12-8-10-15-27-24-30(38-3)33(41-6)31(25-27)39-4;;/h9-10,14-15,22-25H,7-8,11-13,16-21H2,1-6H3;2*1H/b14-9+,15-10+;; |
| Cas号 | 191089-59-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
