JNK-IN-8
编号: 16123027
Cas号: 1410880-22-6
纯度: 98%
JNK-IN-8, also known as JNK Inhibitor XVI, is a selective JNK inhibitor that inhibits phosphorylation of c-Jun, a direct substrate of JNK, in cells exposed to submicromolar drug in a manner that depends on covalent modification of the conserved cysteine residue. Extensive biochemical, cellular, and pathway-based profiling establish the selectivity of JNK-IN-8 for JNK and suggests that the compound will be broadly useful as a pharmacological probe of JNK-dependent signal transduction.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | JNK-IN-8 |
|---|---|
| Iupac 化学名称 | JNK-IN-8 |
| 同义词 | JNK-IN 8; JNK-IN8; JNK Inhibitor XVI; c-Jun N-terminal Kinase Inhibitor XVI |
| 英文同义词 | JNK-IN 8; JNK-IN8; JNK Inhibitor XVI; c-Jun N-terminal Kinase Inhibitor XVI |
| 分子式 | C29H29N7O2 |
| 分子量 | 507.598 |
| Smile | Cc1cc(ccc1Nc2nccc(n2)c3cccnc3)NC(=O)c4cccc(c4)NC(=O)/C=C/CN(C)C |
| InChiKey | GJFCSAPFHAXMSF-UXBLZVDNSA-N |
| InChi | InChI=1S/C29H29N7O2/c1-20-17-24(11-12-25(20)34-29-31-15-13-26(35-29)22-8-5-14-30-19-22)33-28(38)21-7-4-9-23(18-21)32-27(37)10-6-16-36(2)3/h4-15,17-19H,16H2,1-3H3,(H,32,37)(H,33,38)(H,31,34,35)/b10-6+ |
| Cas号 | 1410880-22-6 |
| MDL | MFCD22124890 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
