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IWP-2

Catalog No.: 110602
Cas No.: 686770-61-6
Purity : 98% 
110602 - IWP-2 | CAS 686770-61-6

Catalog number : 110602

CAS number : 686770-61-6

分子式 : C22H18N4O2S3 

分子量 : 466.599 

Iupac 化学名称 : N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide 

Smile : CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

InChiKey : WRKPZSMRWPJJDH-UHFFFAOYSA-N

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同义词IWP 2 
英文同义词IWP 2 
分子式C22H18N4O2S3 
分子量466.599 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4
InChiKeyWRKPZSMRWPJJDH-UHFFFAOYSA-N
InChiInChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)
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IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC₅₀ = 27 nM) by inhibition of the O-acyltransferase Porcn. 

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