HUHS015
编号: 16062902
Cas号: 1453097-13-6
纯度: 98% by HPLC
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expected, continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects.
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化学信息
| 名称 | HUHS015 |
|---|---|
| Iupac 化学名称 | 4-benzyl-3-methyl-1-(5-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-5-ol |
| 同义词 | HUHS 015;HUHS-015 |
| 英文同义词 | HUHS 015;HUHS-015 |
| 分子式 | C19H18N4O |
| 分子量 | 318.37242 |
| Smile | C(C1=CC=CC=C1)C=1C(=NN(C1O)C1=NC2=C(N1)C=CC(=C2)C)C |
| InChiKey | LFEFEOLVKXXVGD-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H18N4O/c1-12-8-9-16-17(10-12)21-19(20-16)23-18(24)15(13(2)22-23)11-14-6-4-3-5-7-14/h3-10,24H,11H2,1-2H3,(H,20,21) |
| Cas号 | 1453097-13-6 |
| 相关CAS号 |
订购信息
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