HS-173
编号: 161009001
Cas号: 1276110-06-5
纯度: 98% by HPLC
HS-173 inhibited the PI3K signaling pathway, and showed anti-proliferative effects on cancer cells. Also, HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis. In addition, HS-173 decreased the expression HIF-1 and VEGF which play an important role in angiogenesis. This effect was confirmed by the suppression of tube formation and migration assay in vitro. Furthermore, HS-173 diminished blood vessel formation in the Matrigel plug assay in mice. Therefore, HS-173 is considered as a novel drug candidate to treat cancer patients.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | HS-173 |
|---|---|
| Iupac 化学名称 | ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate |
| 同义词 | HS173; HS 173; HS-173. |
| 英文同义词 | HS173; HS 173; HS-173. |
| 分子式 | C21H18N4O4S |
| 分子量 | 422.46 |
| Smile | C1(=CC=CC=C1)S(=O)(=O)NC=1C=C(C=NC1)C=1C=CC=2N(C1)C(=CN2)C(=O)OCC |
| InChiKey | SEKOTFCHZNXZMM-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H18N4O4S/c1-2-29-21(26)19-13-23-20-9-8-15(14-25(19)20)16-10-17(12-22-11-16)24-30(27,28)18-6-4-3-5-7-18/h3-14,24H,2H2,1H3 |
| Cas号 | 1276110-06-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
