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Giredestrant

编号: 21248
Cas号: 1953133-47-5
纯度: ≧98.0%

Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.

仅供研究使用。 我们不向患者出售。

化学信息

名称Giredestrant
Iupac 化学名称3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol
同义词GDC-9545 ; GDC9545 ; GDC 9545 ; RG6171 ; RG-6171 ; RG 6171 ; Giredestrant ;
英文同义词GDC-9545 ; GDC9545 ; GDC 9545 ; RG6171 ; RG-6171 ; RG 6171 ; Giredestrant ;
分子式C27H31F5N4O
分子量522.564
SmileC[C@@H]1CC(C2=C(N3)C=CC=C2)=C3[C@@H](C4=C(C=C(C=C4F)NC5CN(C5)CCCF)F)N1CC(CO)(F)F
InChiKeyGQCXHIKRWBIQMD-AKJBCIBTSA-N
InChiInChI=1S/C27H31F5N4O/c1-16-9-20-19-5-2-3-6-23(19)34-25(20)26(36(16)14-27(31,32)15-37)24-21(29)10-17(11-22(24)30)33-18-12-35(13-18)8-4-7-28/h2-3,5-6,10-11,16,18,26,33-34,37H,4,7-9,12-15H2,1H3/t16-,26-/m1/s1
Cas号1953133-47-5
相关CAS号1953133-47-5

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状黄色固体粉末
纯度≧98.0%
存储短期(几天到几周)为0-4摄氏度,长期(几个月)为-20摄氏度
可溶性可溶于DMSO
处理方式Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
运输条件作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

21248 - Giredestrant | CAS 1953133-47-5

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