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GW788388

Catalog No.: 52305
Cas No.: 452342-67-5
Purity : 98% 
52305 - GW788388 | CAS 452342-67-5

Catalog number : 52305

CAS number : 452342-67-5

分子式 : C25H23N5O2 

分子量 : 425.48 

Iupac 化学名称 : 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide 

Smile : O=C(NC1CCOCC1)C2=CC=C(C3=NC=CC(C4=CNN=C4C5=NC=CC=C5)=C3)C=C2

InChiKey : SAGZIBJAQGBRQA-UHFFFAOYSA-N

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同义词GW788388;GW-788388 
英文同义词GW788388;GW-788388 
分子式C25H23N5O2 
分子量425.48 
外观crystalline solid 
纯度98% 
可溶性2mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileO=C(NC1CCOCC1)C2=CC=C(C3=NC=CC(C4=CNN=C4C5=NC=CC=C5)=C3)C=C2
InChiKeySAGZIBJAQGBRQA-UHFFFAOYSA-N
InChiInChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)
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GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibits TGF- type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor. 

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