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GW 627368

Catalog No.: 91003
Cas No.: 439288-66-1
Purity : 98% 

GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 M. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 M. 

For research use only. We do not sell to patients.

Chemical Information

名称GW 627368
同义词4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide 
英文同义词4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide 
分子式C30H28N2O6S 
分子量544.6 
SmileCCOc1c2ccccc2c(c3c1CN(C3=O)c4ccc(cc4)CC(=O)NS(=O)(=O)c5ccccc5)OCC
InChiKeyXREWXJVMYAXCJV-UHFFFAOYSA-N
InChiInChI=1S/C30H28N2O6S/c1-3-37-28-23-12-8-9-13-24(23)29(38-4-2)27-25(28)19-32(30(27)34)21-16-14-20(15-17-21)18-26(33)31-39(35,36)22-10-6-5-7-11-22/h5-17H,3-4,18-19H2,1-2H3,(H,31,33)
Cas号439288-66-1
MDLMFCD12912327
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Ordering Information

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FormulationCrystalline Solid 
纯度98% 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
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Chemical Structure

91003 - GW 627368 | CAS 439288-66-1

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