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GSK2656157

Catalog No.: 52019
Cas No.: 1337532-29-2
Purity : 98% 
52019 - GSK2656157 | CAS 1337532-29-2

Catalog number : 52019

CAS number : 1337532-29-2

分子式 : C23H21FN6O 

分子量 : 416.45 

Iupac 化学名称 : 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone 

Smile : NC=1C2=C(N=CN1)N(C=C2C=2C(=C1CCN(C1=CC2)C(CC2=NC(=CC=C2)C)=O)F)C

InChiKey : PRWSIEBRGXYXAJ-UHFFFAOYSA-N

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同义词N/A 
英文同义词N/A 
分子式C23H21FN6O 
分子量416.45 
外观off-white solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature 
SmileNC=1C2=C(N=CN1)N(C=C2C=2C(=C1CCN(C1=CC2)C(CC2=NC(=CC=C2)C)=O)F)C
InChiKeyPRWSIEBRGXYXAJ-UHFFFAOYSA-N
InChiInChI=1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,27)
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GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM, 500-fold greater against a panel of 300 kinases. 

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