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GSK2334470

Catalog No.: 192224
Cas No.: 1227911-45-6
Purity : >98%

GSK2334470是一种有效的3-磷酸肌苷依赖性蛋白激酶(PDK1)抑制剂(IC50 ~ 10nm),在500倍浓度下不抑制93种其他蛋白激酶的活性,其中13种AGC-激酶与PDK1最相关。

For research use only. We do not sell to patients.

Chemical Information

名称GSK2334470
Iupac 化学名称(3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide
同义词GSK2334470; GSK 2334470; GSK-2334470
英文同义词GSK2334470; GSK 2334470; GSK-2334470
分子式C25H34N8O
分子量462.59
SmileO=C([C@@H]1CN(C2=NC(NC)=NC(C3=CC4=C(C=C3)C(N)=NN4)=C2)[C@H](C)CC1)NC5CCCCC5
InChiKeyQLPHOXTXAKOFMU-WBVHZDCISA-N
InChiInChI=1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13,15,17-18H,3-9,14H2,1-2H3,(H,28,34)(H3,26,31,32)(H,27,29,30)/t15-,17+/m1/s1
Cas号1227911-45-6
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Ordering Information

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Formulation 类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

192224 - GSK2334470  | CAS 1227911-45-6

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