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GSK-2256098

Catalog No.: 16123011
Cas No.: 1224887-10-8
Purity : 98% 
16123011 - GSK-2256098 | CAS 1224887-10-8

Catalog number : 16123011

CAS number : 1224887-10-8

分子式 : C20H23ClN6O2 

分子量 : 414.894 

Iupac 化学名称 : GSK-2256098 

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同义词GSK2256098; GSK 2256098; GSK-2256098; GTPL7939; GTPL-7939; GTP L7939 
英文同义词GSK2256098; GSK 2256098; GSK-2256098; GTPL7939; GTPL-7939; GTP L7939 
分子式C20H23ClN6O2 
分子量414.894 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor GSK2256098 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thereby inhibiting tumor cell migration, proliferation and survival, and tumor angiogenesis. The tyrosine kinase FAK is normally activated by binding to integrins in the extracellular matrix (ECM) but may be upregulated and constitutively activated in various tumor cell types. 

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