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GDC-0853

编号: 16123004
Cas号: 1434048-34-6
纯度: 98% 

GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, which leads to the inhibition of the growth of malignant B-cells that overexpress BTK. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B-lymphocyte development, activation, signaling, proliferation and survival. 

仅供研究使用。 我们不向患者出售。

化学信息

名称GDC-0853
Iupac 化学名称GDC-0853 
同义词GDC 0853; GDC0853; RG-7845; RG7845; RG 7845 
英文同义词GDC 0853; GDC0853; RG-7845; RG7845; RG 7845 
分子式C37H44N8O4 
分子量664.811 
InChiKey
InChi
Cas号1434048-34-6
相关CAS号

订购信息

包装价格库存纯度备货期
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16123004 - GDC-0853 | CAS 1434048-34-6

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