Fulacimstat
编号: 2071514
Cas号: 1488354-15-9
纯度: 98% Min.
Fulacimstat, also known as BAY1142524, is a chymase inhibitor and antifibrotic drug candidate with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively. The orally available chymase inhibitor BAY 1142524 is currently being developed as a first-in-class treatment for left-ventricular dysfunction after myocardial infarction.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Fulacimstat |
|---|---|
| Iupac 化学名称 | 1-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)- 2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden- 1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid |
| 同义词 | Fulacimstat; BAY1142524; BAY-1142524; BAY 1142524; |
| 英文同义词 | Fulacimstat; BAY1142524; BAY-1142524; BAY 1142524; |
| 分子式 | C23H16F3N3O6 |
| 分子量 | 487.39 |
| Smile | O=C(C1=CN(C2=CC=C3N(C)C(OC3=C2)=O)C(N([C@@H]4CCC5=C4C=CC=C5C(F)(F)F)C1=O)=O)O |
| InChiKey | JDARDSVOVYVQST-MRXNPFEDSA-N |
| InChi | InChI=1S/C23H16F3N3O6/c1-27-17-7-5-11(9-18(17)35-22(27)34)28-10-14(20(31)32)19(30)29(21(28)33)16-8-6-12-13(16)3-2-4-15(12)23(24,25)26/h2-5,7,9-10,16H,6,8H2,1H3,(H,31,32)/t16-/m1/s1 |
| Cas号 | 1488354-15-9 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
