Flavopiridol(Alvocidib)
编号: 52310
Cas号: 131740-09-5
纯度: 98%
Flavopiridol HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Flavopiridol(Alvocidib) |
|---|---|
| Iupac 化学名称 | 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride |
| 同义词 | HL 275; NSC 649890; MDL 107826A; FLAVOPIRIDOL HCL; Alvocidib Hydrochloride |
| 英文同义词 | HL 275; NSC 649890; MDL 107826A; FLAVOPIRIDOL HCL; Alvocidib Hydrochloride |
| 分子式 | C21H20ClNO5.HCl |
| 分子量 | 438.3 |
| Smile | O=C1C=C(C2=CC=CC=C2Cl)OC3=C1C(O)=CC(O)=C3[C@@H]4[C@H](O)CN(C)CC4.[H]Cl |
| InChiKey | LGMSNQNWOCSPIK-LWHGMNCYSA-N |
| InChi | InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22;/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3;1H/t12-,17+;/m0./s1 |
| Cas号 | 131740-09-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
-cas-131740-09-5.png)