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Firategrast

Catalog No.: 16122946
Cas No.: 402567-16-2
Purity : 98% 

Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). This could decrease multiple sclerosis (MS) activity, but may compromise CNS immune surveillance. The integrins are a sort of transmembrane receptors that modulate the signal transduction from ECM to the cell. They are associated with a lot of diseases such as cancer, inflammation and thrombotic diseases. 

For research use only. We do not sell to patients.

Chemical Information

名称Firategrast
Iupac 化学名称Firategrast 
同义词SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047 
英文同义词SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047 
分子式C27H27F2NO6 
分子量499.5108 
SmileCCOCc1cc(c(c(c1)OC)c2ccc(cc2)C[C@@H](C(=O)O)NC(=O)c3c(cccc3F)F)OC
InChiKeyYLFZHHDVRSYTKT-NRFANRHFSA-N
InChiInChI=1S/C27H27F2NO6/c1-4-36-15-17-13-22(34-2)24(23(14-17)35-3)18-10-8-16(9-11-18)12-21(27(32)33)30-26(31)25-19(28)6-5-7-20(25)29/h5-11,13-14,21H,4,12,15H2,1-3H3,(H,30,31)(H,32,33)/t21-/m0/s1
Cas号402567-16-2
MDLMFCD19443754
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Ordering Information

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Formulationcrystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122946 - Firategrast | CAS 402567-16-2

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