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Filgotinib

Catalog No.: 51612
Cas No.: 1206161-97-8
Purity : 98% 
51612 - Filgotinib | CAS 1206161-97-8

Catalog number : 51612

CAS number : 1206161-97-8

分子式 : C21H23N5O3S 

分子量 : 425.50 

Iupac 化学名称 : N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide 

Smile : O=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2

InChiKey : RIJLVEAXPNLDTC-UHFFFAOYSA-N

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同义词GLPG0634;GLPG-0634 
英文同义词GLPG0634;GLPG-0634 
分子式C21H23N5O3S 
分子量425.50 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileO=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2
InChiKeyRIJLVEAXPNLDTC-UHFFFAOYSA-N
InChiInChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)
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Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2. 

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