FRAX597
编号: 72803
Cas号: 1286739-19-2
纯度: 97%
FRAX597 inhibits the proliferation of NF2-deficient schwannoma cells in culture and displayed potent anti-tumor activity in vivo, impairing schwannoma development in an orthotopic model of NF2. These studies identify a novel class of orally available ATP-competitive Group I PAK inhibitors with significant potential for the treatment of NF2 and other cancers.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | FRAX597 |
|---|---|
| Iupac 化学名称 | 6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one |
| 同义词 | FRAX 597; FRAX-597 |
| 英文同义词 | FRAX 597; FRAX-597 |
| 分子式 | C29H28ClN7OS |
| 分子量 | 558.10 |
| Smile | ClC1=C(C=CC(=C1)C1=CN=CS1)C1=CC2=C(N=C(N=C2)NC2=CC=C(C=C2)N2CCN(CC2)C)N(C1=O)CC |
| InChiKey | DHUJCQOUWQMVCG-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H28ClN7OS/c1-3-37-27-20(14-24(28(37)38)23-9-4-19(15-25(23)30)26-17-31-18-39-26)16-32-29(34-27)33-21-5-7-22(8-6-21)36-12-10-35(2)11-13-36/h4-9,14-18H,3,10-13H2,1-2H3,(H,32,33,34) |
| Cas号 | 1286739-19-2 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
