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FRAX486

Catalog No.: 18721
Cas No.: 1232030-35-1
Purity : >98%

FRAX486是一种有效的p21激活激酶(PAK)抑制剂(PAK1、PAK2、PAK3和PAK4的IC50值分别为14、33、39和575 nM)。

For research use only. We do not sell to patients.

Chemical Information

名称FRAX486
Iupac 化学名称6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
同义词FRAX486; FRAX-486; FRAX 486.
英文同义词FRAX486; FRAX-486; FRAX 486.
分子式C25H23Cl2FN6O
分子量513.4
SmileO=C1C(C2=CC=C(Cl)C=C2Cl)=CC3=CN=C(NC4=CC=C(N5CCNCC5)C(F)=C4)N=C3N1CC
InChiKeyDHKFOIHIUYFSOF-UHFFFAOYSA-N
InChiInChI=1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6,11-14,29H,2,7-10H2,1H3,(H,30,31,32)
Cas号1232030-35-1
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Ordering Information

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Formulation 类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

18721 - FRAX486 | CAS 1232030-35-1

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