+86-27-65522453 sales@sun-shinechem.com

FIIN-3

Catalog No.: 16122945
Cas No.: 1637735-84-2
Purity : 98% 
16122945 - FIIN-3 | CAS 1637735-84-2

Catalog number : 16122945

CAS number : 1637735-84-2

分子式 : C34H36Cl2N8O4 

分子量 : 691.60684 

Iupac 化学名称 : FIIN-3 

InChiKey :

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词FIIN3; FIIN 3 
英文同义词FIIN3; FIIN 3 
分子式C34H36Cl2N8O4 
分子量691.60684 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
InChiKey
InChi
Coming soon.
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-3 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. FIIN-3 has the unprecedented ability to inhibit both the EGF receptor (EGFR) and FGFR covalently by targeting two distinct cysteine residues. FIIN-3 bound with FGFR4 V550L and EGFR L858R. (Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4869-77.) 

1637735-84-2 - Request Bulk Quote

×
1637735-84-2 - Request Bulk Quote
Change