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FH535

编号: 16122788
Cas号: 108409-83-2
纯度: 98% 

FH535 is a Wnt/-catenin signaling inhibitor and also a dual PPAR and PPAR antagonist.FH535 antagonizes -Catenin/TcfCmediated transcription, and inhibits recruitment of the coactivators GRIP1 and -catenin to PPAR and PPAR. FH535 shows selective anti-proliferation effect on some cancer cells expressing high or active Wnt/-catenin pathway. [1] FH535 increases cigarette smoke condensate cytotoxicity, and causes changes in -catenin and EGR-1 signaling. [2] FH535 has potential therapeutic value in treatment of liver cancer by targeting liver cancer stem cells and hepatocellular carcinoma cell lines.  

仅供研究使用。 我们不向患者出售。

化学信息

名称FH535
Iupac 化学名称FH535 
同义词N/A 
英文同义词N/A 
分子式C13H10Cl2N2O4S 
分子量361.2 
SmileCc1cc(ccc1NS(=O)(=O)c2cc(ccc2Cl)Cl)[N+](=O)[O-]
InChiKeyAXNUEXXEQGQWPA-UHFFFAOYSA-N
InChiInChI=1S/C13H10Cl2N2O4S/c1-8-6-10(17(18)19)3-5-12(8)16-22(20,21)13-7-9(14)2-4-11(13)15/h2-7,16H,1H3
Cas号108409-83-2
MDLMFCD01212888
相关CAS号

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122788 - FH535 | CAS 108409-83-2

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