FH535
编号: 16122788
Cas号: 108409-83-2
纯度: 98%
FH535 is a Wnt/-catenin signaling inhibitor and also a dual PPAR and PPAR antagonist.FH535 antagonizes -Catenin/TcfCmediated transcription, and inhibits recruitment of the coactivators GRIP1 and -catenin to PPAR and PPAR. FH535 shows selective anti-proliferation effect on some cancer cells expressing high or active Wnt/-catenin pathway. [1] FH535 increases cigarette smoke condensate cytotoxicity, and causes changes in -catenin and EGR-1 signaling. [2] FH535 has potential therapeutic value in treatment of liver cancer by targeting liver cancer stem cells and hepatocellular carcinoma cell lines.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | FH535 |
|---|---|
| Iupac 化学名称 | FH535 |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C13H10Cl2N2O4S |
| 分子量 | 361.2 |
| Smile | Cc1cc(ccc1NS(=O)(=O)c2cc(ccc2Cl)Cl)[N+](=O)[O-] |
| InChiKey | AXNUEXXEQGQWPA-UHFFFAOYSA-N |
| InChi | InChI=1S/C13H10Cl2N2O4S/c1-8-6-10(17(18)19)3-5-12(8)16-22(20,21)13-7-9(14)2-4-11(13)15/h2-7,16H,1H3 |
| Cas号 | 108409-83-2 |
| MDL | MFCD01212888 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
