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FG-2216

Catalog No.: 16122812
Cas No.: 223387-75-5
Purity : 98% 
16122812 - FG-2216 | CAS 223387-75-5

Catalog number : 16122812

CAS number : 223387-75-5

分子式 : C12H9ClN2O4 

分子量 : 280.664 

Iupac 化学名称 : FG-2216 

Smile : c1ccc2c(c1)c(c(nc2Cl)C(=O)NCC(=O)O)O

InChiKey : OUQVKRKGTAUJQA-UHFFFAOYSA-N

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同义词FG 2216; FG2216; YM311; YM-311; YM 311 
英文同义词FG 2216; FG2216; YM311; YM-311; YM 311 
分子式C12H9ClN2O4 
分子量280.664 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
Smilec1ccc2c(c1)c(c(nc2Cl)C(=O)NCC(=O)O)O
InChiKeyOUQVKRKGTAUJQA-UHFFFAOYSA-N
InChiInChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17)
MDLMFCD23136998
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FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. FG-2216 showed the ability to stabilize HIF-, to stimulate EPO secretion in in vitro studies, and to increase hematocrit, red blood cell count, and hemoglobin levels in an animal efficacy study. 

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