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Etamicastat HCl salt

Catalog No.: 16071009
Cas No.: 677773-32-9
Purity : 98% by HPLC 

Etamicastat, also known as BIA 5-453, is a potent, reversible, peripherally selective dopamine -hydroxylase inhibitor (DBH inhibitor). Chronic dopamine ß-hydroxylase inhibition with etamicastat effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat. 

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Chemical Information

名称Etamicastat HCl salt
Iupac 化学名称(R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride 
同义词BIA 5-453; BIA5-453 
英文同义词BIA 5-453; BIA5-453 
分子式C14H16ClF2N3OS 
分子量347.8088 
SmileCl.NCCC1=CNC(N1[C@H]1COC2=C(C=C(C=C2C1)F)F)=S
InChiKeyCKRDOSZCFINPAD-RFVHGSKJSA-N
InChiInChI=1S/C14H15F2N3OS.ClH/c15-9-3-8-4-11(7-20-13(8)12(16)5-9)19-10(1-2-17)6-18-14(19)21;/h3,5-6,11H,1-2,4,7,17H2,(H,18,21);1H/t11-;/m1./s1
Cas号677773-32-9
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16071009 - Etamicastat HCl salt | CAS 677773-32-9

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