Welcome to Sun-shine chemical
+86-27-65522453 sales@sun-shinechem.com

Elesclomol

Catalog No.: 16071025
Cas No.: 488832-69-5
Purity : 98% by HPLC 

Elesclomol, also known as STA-4783, is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway.  

For research use only. We do not sell to patients.

Chemical Information

名称Elesclomol
Iupac 化学名称N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide 
同义词STA4783; STA-4783 
英文同义词STA4783; STA-4783 
分子式C19H20N4O2S2 
分子量400.52 
SmileCN(NC(CC(=O)NN(C(=S)C1=CC=CC=C1)C)=O)C(=S)C1=CC=CC=C1
InChiKeyBKJIXTWSNXCKJH-UHFFFAOYSA-N
InChiInChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)
Cas号488832-69-5
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS 电话 : +86-27-65522453   Email : sales@sun-shinechem.com
FormulationSolid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16071025 - Elesclomol | CAS 488832-69-5

Quick inquiry

Change